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藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73296c-Kit A502_Y503dup/BaF3

- 詳細(xì)內(nèi)容
CBP73296 | |
I. Introduction | |
Cell Line Name: | c-Kit A502_Y503dup/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
II. Background | |
KIT A502_Y503dup (also referred to as Y503_F504insAY) indicates the insertion of 2 duplicate amino acids, alanine (A)-502 through tyrosine (Y)-503, in the Ig-like C2-type domain 5 (exon 9) of the Kit protein . A502_Y503dup results in constitutive phosphorylation of Kit and is transforming in cell culture. | |
III. Representative Data | |
1. WB of c-Kit A502_Y503dup/BaF3 | |
2. Sanger of c-Kit A502_Y503dup/BaF3 | |
3. Anti-proliferation assay Figure 4. CTG Proliferation Assay of BaF3 C-KIT A502_Y503dup Cells (C5). |