名稱 | CCDC6-RET WT/BaF3 |
型號(hào) | CBP73214 |
報(bào)價(jià) | |
特點(diǎn) | CCDC6-RET WT/BaF3,母細(xì)胞:BaF3 |
產(chǎn)品搜索
相關(guān)文章
聯(lián)系我們
電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73214CCDC6-RET WT/BaF3
- 詳細(xì)內(nèi)容
CBP73214 | |
I. Introduction | |
Cell Line Name: | CCDC6-RET WT/BaF3 |
Host Cell: | BA/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS+1ug/ml puromycin |
Mycoplasma Status: | Negative |
II.Background | |
CCDC6, coiled-coil domain containing 6, has been shown to play a role in the DNA damaging signaling pathway acting as a substrate of ATM (PMID: 17420723). CCDC6 fusions with RET (PMID: 23154560, PMID: 26078337) and BRAF (PMID: 26314551) have been observed in multiple cancer types. | |
III. Representative Data | |
1. WB of CCDC6-RET WT/BaF3WT | |
2. Sanger of CCDC6-RET WT/BaF3 Figure 2. Breakpoint of CCDC6-RET WT/BaF3 | |
2. Anti-proliferation assay | |
Figure 3. CTG assay of for CCDC6-RET WT/BaF3 Stable Cell Line,the Gi50 was 137.3nM. |