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藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73252CSF3R T615A/BaF3

CSF3R T615A/BaF3
名稱 CSF3R T615A/BaF3
型號(hào) CBP73252
報(bào)價(jià)
特點(diǎn) CSF3R T615A/BaF3,母細(xì)胞:BaF3,CSF3R T615A 位于 Csf3r 蛋白跨膜結(jié)構(gòu)域附近的胞外結(jié)構(gòu)域內(nèi)(PMID:23656643)。預(yù)計(jì) T615A 會(huì)增強(qiáng) Csf3r 蛋白的功能,如培養(yǎng)物中轉(zhuǎn)化細(xì)胞增殖增加所證明的 (PMID: 23656643)。
  • 詳細(xì)內(nèi)容

CBP73252

I. Introduction

Cell Line Name:

CSF3R T615A/BaF3

Host Cell:

Ba/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS

Mycoplasma Status:

Negative

II.Background

CSF3R T615A lies within the extracellular domain proximal to the transmembrane domain of the Csf3r protein (PMID: 23656643). T615A is predicted to confer a gain of function to the Csf3r protein, as demonstrated by increased proliferation of transformed cells in culture (PMID: 23656643).

III. Representative Data

1.WB of  CSF3R T615A/BaF3

CBP73252 WB.png


2. Anti-proliferation assay

CBP73252-2.jpg


Figure 2. Anti-proliferation assay of three reference compounds on the CSF3R T615A/BaF3.


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