名稱(chēng) | FLT3-ITD D835del/BaF3 |
型號(hào) | CBP73241 |
報(bào)價(jià) | ![]() |
特點(diǎn) | FLT3-ITD [D835del]/BaF3,母細(xì)胞:BaF3,凍存條件:90% FBS+10% DMSO |
產(chǎn)品搜索
產(chǎn)品分類(lèi)
相關(guān)文章
- STING激動(dòng)劑和拮抗劑的篩選
- “鉆石突變”ALK基因診斷
- 細(xì)胞株的一些篩選事項(xiàng)為您解讀
- PNAS:腫瘤細(xì)胞或可“拆用”間充質(zhì)干細(xì)胞來(lái)促進(jìn)乳腺癌復(fù)發(fā)
- 抑制性檢查點(diǎn)靶點(diǎn)及其細(xì)胞篩選模型
- 腫瘤細(xì)胞培養(yǎng)實(shí)驗(yàn)的主要用途
- 降糖+減肥?GIPR靶點(diǎn)研究進(jìn)展
- 【產(chǎn)品推介】NRAS診斷標(biāo)準(zhǔn)品
- 【產(chǎn)品推介】胰高血糖素受體藥物細(xì)胞篩選模型
- 鑒別ATCC細(xì)胞株真?zhèn)蔚姆椒?/a>
聯(lián)系我們
電話(huà):4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73241FLT3-ITD D835del/BaF3
![FLT3-ITD D835del/BaF3](http://img80.chem17.com/gxhpic_a89b1029a6/fd9c5b6de14e75b1eafd7ea18ebce581b3ffb67da0e34310505290994c621a9eb8eec7d9fa03e8d2.jpg)
- 詳細(xì)內(nèi)容
CBP73241 | |
I. Introduction | |
Cell Line Name: | FLT3-ITD [D835del]/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS+2ug/ml puromycin |
Mycoplasma Status: | Negative |
II.Background | |
FLT3, receptor-type tyrosine-protein kinase FLT3, activates Akt, Ras, and Erk pathways to regulate differentiation, proliferation, and survival of hematopoietic progenitor cells (PMID: 29316714, PMID: 28538663). Activating mutations of FLT3 are common in hematologic tumors (PMID: 19467916) and the internal tandem duplication (ITD) mutation is commonly observed in acute myeloid leukemia (PMID: 30181385). | |
III. Representative Data | |
1.FLT3-ITD [D835del]/BaF3 | |
2. Anti-proliferation assay | |
Figure . Anti-proliferation assay of three reference compounds on the FLT3-ITD [D835del]/BaF3 Stable Cell Line. |