名稱 | CSF1R/SRE-Luc/HEK293 |
型號(hào) | CBP74010 |
報(bào)價(jià) | ![]() |
特點(diǎn) | CSF1R/SRE-Luc/HEK293,凍存條件:90% FBS+10% DMSO |
產(chǎn)品搜索
相關(guān)文章
- 抑制性檢查點(diǎn)靶點(diǎn)及其細(xì)胞篩選模型
- 北京細(xì)胞庫(kù)關(guān)于細(xì)胞存儲(chǔ)的意義了解下
- FGFR2融合靶向藥物細(xì)胞篩選模型
- ?LILRB4細(xì)胞篩選模型
- 增強(qiáng)腫瘤免疫療法新靶點(diǎn):ADORA2B(腺苷A2B受體)
- 你知道ATCC細(xì)胞如何解凍嗎?
- 【產(chǎn)品推介】TERT診斷標(biāo)準(zhǔn)品
- 分子診斷標(biāo)準(zhǔn)品,匠心出品,免費(fèi)申領(lǐng)
- 聚焦靶點(diǎn)BRAF——BRAF相關(guān)突變細(xì)胞強(qiáng)勢(shì)登場(chǎng)
- GLP-1R、GCGR、GIPR多靶點(diǎn)激動(dòng)劑與代謝疾病
聯(lián)系我們
電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > 腫瘤免疫細(xì)胞株 > CBP74010CSF1R/SRE-Luc/HEK293

- 詳細(xì)內(nèi)容
I. Background | |
集落刺激因子 1(Colony Stimulating Factor 1,CSF1),又稱巨噬細(xì)胞集落刺激因 子(M-CSF),是由兩條相同多肽鏈通過(guò)二硫鍵形成的同源二聚體,是導(dǎo)致各種炎癥性疾 病的最常見(jiàn)的促炎細(xì)胞因子之一。其在骨關(guān)節(jié)炎、癌癥和其他自身免疫性疾病的發(fā)展和進(jìn) 展中具有顯著的作用。 | |
II. Desription | |
CSF1R SRE-Luc HEK293 報(bào)告基因藥靶模型很好的模擬了體內(nèi) CSF1 的信號(hào)轉(zhuǎn)導(dǎo)過(guò)程, 原理見(jiàn)下圖所示。 Figure 1. CSF1R SRE-Luc HEK293 細(xì)胞模型原理圖 | |
Ⅱ. Introduction | |
Host Cell: | HEK293 |
Expressed gene: | CFS1R-SRE-Luciferase |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Synonym(s): | FMS, CD115 |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | DMEM+10%FBS+200 μg/ml Hygromycin B+1 μg/ml Puromycin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
Application(s): | Functional(Report Gene) Assay |
Ⅲ. Description of Host Cell Line | |
Organism: | Human |
Tissue: | Embryonic kidney |
Morphology: | Epitheloid cell |
Growth Properties: | Adherent |
Ⅳ. Representative Data |
Figure 2. Recombinant CSF1R/SRE-Luc/HEK293 stably expressing CSF1R.
Figure 3. Detect Luciferase assay by Ultra Luciferase Detection Kit CBPH0001(we strongly suggest to purchase from Cobioer). Dose Response of Recombinant Human CSF1 in CSF1R SRE-Luc HEK293(C2).
Figure 4. Inhibition of Human CSF1-induced Reporter Activity by CPDs in SRE-Luc HEK293(C2).