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藥靶細(xì)胞株 > 腫瘤免疫細(xì)胞株 > CBP74114hIL11 Effector Reporter Cell

hIL11 Effector Reporter Cell
名稱 hIL11 Effector Reporter Cell
型號(hào) CBP74114
報(bào)價(jià)
特點(diǎn) hIL11 Effector Reporter Cell，凍存條件：90% FBS+10% DMSO；
  • 詳細(xì)內(nèi)容


CBP74114
I. Background
IL-11 is secreted by bone marrow stromal cells (fibroblasts)and is produced also by a number of mesenchymal cells. The IL-11 receptor (alpha chain) utilizes gp130 as its signal transducer, which is also a component of other cytokine receptors. The alpha chain of the IL-11 receptor has been identified independently as Etl2. IL-11 promotes primary and secondary immune responses in vitro and in vivo and modulates antigen-specific antibody reactions. IL-11 promotes the proliferation of IL-6 dependent plasmacytoma cell lines in the presence of neutralizing IL-6 antibodies. IL-11 also stimulates the T-cell dependent development of IgG-secreting B-cells in spleen cell cultures. IL-11 inhibits the differentiation of pre- adipocytes. It induces the synthesis of some acute phase proteins by hepatocytes.
II. Introduction
Expressed gene:hIL11 
Stability:32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s):IL-11, IL11, Oprelvekin, Interleukin-11
Freeze Medium:90% FBS+10% DMSO
Culture Medium:DMEM + 10%FBS+200ug/ml hygromycin+1ug/ml puromycin
Mycoplasma Testing:Negative
Storage:Liquid nitrogen
Application(s):Functional(Report Gene) Assay
III. Representative Data

COBIOER

Figure 1.hIL11 Induced Reporter Activity of hIL11 Effector Reporter Cell.





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