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藥靶細(xì)胞株 > GPCR細(xì)胞株 > CBP71363CCR8/β-Arrestin/CHO GPCR細(xì)胞

CCR8/β-Arrestin/CHO GPCR細(xì)胞
名稱 CCR8/β-Arrestin/CHO GPCR細(xì)胞
型號 CBP71363
報價
特點 CCR8/β-Arrestin/CHO
  • 詳細(xì)內(nèi)容
CBP71363
I. Background

C-C chemokine receptor type 1 (CCR8) is a G protein-coupled receptor member of the CC chemokine subfamily of
receptors. Following interaction with its specific chemokine ligands, like macrophage inflammatory protein 1 alpha
(MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), and monocyte
chemoattractant protein 3 (MCP-3), it triggers the onset of a process known as chemotaxis. GenScript’s human
CCR8-expressing stable subline is guaranteed to function properly in the calcium flux assay.

 
II. Introduction
Host Cell:

CHO

Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:N/A
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for CCR8 receptor

Transducer:Gi
 
Ⅲ. Description of Host Cell Line
Organism:Hamster
Tissue:Ovary
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data

CBP71363.png

Figure 1. Dose response of Human Recombinant CCL1 in CCR8 β-Arrestin/CHO-K1 Cell Line (C6).

CBP71363 數(shù)據(jù)圖2.png

Figure 2. Inhibition of CCL1-induced Beta-Arrestin Recruitment By CCR8 Blocking Ab in CCR8 Beta-Arrestin CHO-K1 Cells.

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