名稱 | KRAS p.G12S Reference Standard 標(biāo)準(zhǔn)品 |
型號 | CBP10297 |
報價 | ![]() |
特點(diǎn) | KRAS p.G12S Reference Standard |
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10297KRAS p.G12S Reference Standard 標(biāo)準(zhǔn)品

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CBP10297 | |
Format | Genomic DNA |
Description | KRAS G12S is a hotspot mutation that lies within a GTP binding region of the Kras protein (UniProt.org). G12S results in decreased Kras GTP-GDP exchange rate and leads to increased Ras-GTP and activation of downstream signaling in cell culture (PMID: 23455880, PMID: 28484014, PMID: 26184075). |
Technical Data | |
DNA Change | c.34G>A |
AA Change | p.G12S |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000311936 |
Cosmic ID | COSM517 |
Chr position(GRCh37) | chr12:25398285 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |