名稱(chēng) | NRAS p.Q61K Reference Standard 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10310 |
報(bào)價(jià) | ![]() |
特點(diǎn) | NRAS p.Q61K Reference Standard |
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地址:南京市棲霞區(qū)緯地路9號(hào)
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10310NRAS p.Q61K Reference Standard 標(biāo)準(zhǔn)品

- 詳細(xì)內(nèi)容
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CBP10310 | |
Format | Genomic DNA |
Description | NRAS Q61K is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). Q61K confers a loss of function on Nras protein as indicated by activation of downstream pathway signaling, increased survival, and transformation of cultured cells (PMID: 22718121). |
Technical Data | |
DNA Change | c.181C>A |
AA Change | p.Q61K |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 85.71% |
Transcript | ENST00000369535 |
Cosmic ID | COSM580 |
Chr position(GRCh37) | chr1:115256530 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |