名稱 | PIK3CA p.E453K Reference Standard 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10332 |
報(bào)價(jià) | ![]() |
特點(diǎn) | PIK3CA p.E453K Reference Standard |
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電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10332PIK3CA p.E453K Reference Standard 標(biāo)準(zhǔn)品

- 詳細(xì)內(nèi)容
CBP10332 | |
Format | Genomic DNA |
Description | PIK3CA E453K lies within the C2 PI3K-type domain of the Pik3ca protein (UniProt.org). E453K results in increased phosphorylation of Akt and Mek1/2, enhanced cell survival, and is transforming in culture (PMID: 26627007, PMID: 29533785). |
Technical Data | |
DNA Change | c.1357G>A |
AA Change | p.E453K |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | NM_006218.1 |
Cosmic ID | COSM12584 |
Chr position(GRCh37) | chr3:178928079 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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