名稱 | EGFR V769_D770insGSV/BaF3 |
型號(hào) | CBP73217 |
報(bào)價(jià) | |
特點(diǎn) | EGFR V769_D770insGSV/BaF3,母細(xì)胞:BaF3,凍存條件:90% FBS+10% DMSO |
產(chǎn)品搜索
相關(guān)文章
聯(lián)系我們
電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73217EGFR V769_D770insGSV/BaF3
- 詳細(xì)內(nèi)容
CBP73217 | |
I. Introduction | |
Cell Line Name: | EGFR V769_D770insGSV/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
II.Background | |
EGFR V769_D770insGSV results in the insertion of three amino acids in the protein kinase domain of the Egfr protein between amino acids 769 and 770 (UniProt.org). V769_D770insGSV has not been biochemically characterized, but is predicted to result in a gain of function based on the effect of other Egfr exon 20 insertions (PMID: 24353160). | |
III. Representative Data | |
1. WB of EGFR V769_D770insGSV/BaF3 | |
2. Anti-proliferation assay |