| 名稱 | FLT3-ITD D835V/BaF3 |
| 型號 | CBP73097 |
| 報價 |  |
| 特點 | FLT3-ITD [D835V]/BaF3,母細(xì)胞：BaF3，凍存條件：90% FBS+10% DMSO |
產(chǎn)品搜索
相關(guān)文章
- 拯救偏頭痛！CGRP及其受體拮抗劑研究進(jìn)展
- ATCC細(xì)胞株的特殊性質(zhì)或標(biāo)志必須在整個培養(yǎng)期間始終存在
- 【連載-企業(yè)參考品】 前列腺癌的診斷參考品的選擇
- KIR3DL3/HHLA2細(xì)胞篩選模型
- 重磅！科學(xué)家成功利用免疫細(xì)胞運輸抗癌藥物至腫瘤靶點
- CYP1A1基因多態(tài)性用藥指導(dǎo)標(biāo)準(zhǔn)品
- ANG TIE2：重塑千億血管靶向治療市場，“血管-免疫”協(xié)同治療革命
- 黃金賽道——CDH17靶點
- 免疫治療的下一個靶標(biāo)：腫瘤相關(guān)巨噬細(xì)胞？
- IHC第三方質(zhì)控品——病理質(zhì)控基石，精準(zhǔn)診斷起點
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號碼：
手機：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com
電話：4008750250
號碼：
手機：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73097FLT3-ITD D835V/BaF3
- 詳細(xì)內(nèi)容
| CBP73097 | |
| I. Introduction | |
Cell Line Name： | FLT3-ITD [D835V]/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
| II.Background | |
FLT3, receptor-type tyrosine-protein kinase FLT3, activates Akt, Ras, and Erk pathways to regulate differentiation, proliferation, and survival of hematopoietic progenitor cells (PMID: 29316714, PMID: 28538663). Activating mutations of FLT3 are common in hematologic tumors (PMID: 19467916) and the internal tandem duplication (ITD) mutation is commonly observed in acute myeloid leukemia (PMID: 30181385). | |
| III. Representative Data | |
1.FLT3-ITD [D835V]/BaF3 | |
2. Anti-proliferation assay | |
Figure . Anti-proliferation assay of two reference compounds on the FLT3-ITD [D835V]/BaF3 Stable Cell Line. | |
