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藥靶細(xì)胞株 > 腫瘤免疫細(xì)胞株 > CBP74122SIRPɑ Effector Reporter Cell

SIRPɑ Effector Reporter Cell
名稱 SIRPɑ Effector Reporter Cell
型號 CBP74122
報(bào)價(jià)
特點(diǎn) SIRPɑ Effector Reporter Cell，凍存條件：90% FBS+10% DMSO；
  • 詳細(xì)內(nèi)容


CBP74122
I. Background
SIRP alpha protein, or Signal regulatory proteinalpha (SIRP-α), also known as Tyrosine protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, GenBank Accession No. NM_080792, a.a. 27-370, with C-terminal Avi and His tags, MW 40.3 kDa*. This SIRP alpha protein acts as a receptor for CD47; a.a. 27-370 correspond to the extracellular portion of SIRP-α. *Note: SIRP-α is heavily glycosylated, resulting in higher molecular weight.
II. Introduction
Expressed gene:SIRPɑ
Stability:32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s):SIRP alpha protein, sirpa protein, sirp-a protein, SIRP?±, CD172a, Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, 71138-1, 71138-2
Freeze Medium:90% FBS+10% DMSO
Culture Medium:RPMI-1640+10%FBS+1ug/ml puromycin+300ug/ml hygromycin
Mycoplasma Testing:Negative
Storage:Liquid nitrogen
Application(s):Functional(Report Gene) Assay
III. Representative Data



Figure 1. Dose response of Sirpɑ Blocking Antibodies in SIRPɑ Effector Reporter Cells With CD47+ Target Cells.



Figure 2. Dose response of CD47 Blocking Antibody in SIRPɑ Effector Reporter Cells(C11) With CD47+ Target Cells.





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