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基因檢測標準品 > Mutation > CBP10240BRAF p.L597R Reference Standard 標準品

BRAF p.L597R Reference Standard 標準品
名稱 BRAF p.L597R Reference Standard 標準品
型號 CBP10240
報價 900
特點 BRAF p.L597R Reference Standard
  • 詳細內容



CBP10240
FormatGenomic DNA
DescriptionBRAF L597R lies within the protein kinase domain of the Braf protein (UniProt.org). L597R results in activation of Braf as indicated by increased phosphorylation of Mek and Erk in cell culture (PMID: 22798288, PMID: 26343582), is associated with Erk activation in a patient tumor sample (PMID: 23715574), and in one of two cell lines, increased cell proliferation and cell viability compared to wild-type Braf (PMID: 29533785).
  
Technical Data 
DNA Changec.1790T>G
AA Changep.L597R
Mutation typeSubstitution - Missense
ZygosityHeterozygous
Allelic Frequency50.00%
TranscriptENST00000288602
Cosmic IDCOSM471
Chr position(GRCh37)chr7:140453145
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

10240.png

Storage4℃
Expiry36 months from the date of manufacture


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