名稱 | TP53 p.V274F Reference Standard 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10191 |
報(bào)價(jià) | |
特點(diǎn) | TP53 p.V274F Reference Standard |
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電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10191TP53 p.V274F Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10191 | |
Format | Genomic DNA |
Description | TP53 V274F lies within the DNA-binding domain of the Tp53 protein (PMID: 22713868). V274F results in decreased Tp53 transactivation activity and reduced induction of apoptosis, but retains some context-dependent growth suppression in cell culture (PMID: 12782597). |
Technical Data | |
DNA Change | c.820G>T |
AA Change | p.V274F |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000269305 |
Cosmic ID | COSM10769 |
Chr position(GRCh37) | chr17:7577118 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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