名稱 | KRAS G12C-Q99L/BaF3 Kinase |
型號 | CBP73374 |
報價 | |
特點 | KRAS G12C-Q99L/BaF3,凍存條件:90% FBS+10% DMSO |
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Email: zhangxiangwen@cobioer.com
電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
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藥靶細胞株 > kinase激酶細胞株 > CBP73374KRAS G12C-Q99L/BaF3 Kinase
- 詳細內(nèi)容
CBP73374 | |
I. Introduction | |
Cell Line Name: | KRAS G12C-Q99L/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS+5ug/ml blasticidin |
Mycoplasma Status: | Negative |
II.Background | |
KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118). | |
III. Representative Data | |
1.Sanger of KRAS G12C-Q99L/BaF3 Figure 1. KRAS(NM_033360.4):c.34G>T p.G12C Figure 2. KRAS(NM_004985.5):c.296A>T p.Q99L | |
Figure 3. CTG Proliferation Assay of KRAS G12C/Q99L BaF3 Cells (C4). |