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基因檢測標(biāo)準(zhǔn)品 > 其他類別 > CBP80001-10bTMB-P1 (22.91) Reference Standard

bTMB-P1 (22.91) Reference Standard
名稱 bTMB-P1 (22.91) Reference Standard
型號 CBP80001-10
報價
特點(diǎn) bTMB-P1 (22.91) Reference Standard
  • 詳細(xì)內(nèi)容

 

CBP80001-10
I. Background

Tumor mutational burden (TMB) shows great promise as a biomarker for immuno-oncology (I-O) therapy response, but progress is hindered by the lack of a standardized TMB measurement by targeted NGS panels, and an absence of TMB reference materials. 

 

Sample ID

Cat.No.

Format

Background

Assay

Comments

DC20030079

CBP80001-10N

gDNA

B lymphoblast, Female

500x WES

Same individual

DC20030078

CBP80001-10T

ctDNA (Enzymatic digestion)

stage 4, adenocarcinoma Lung, Female

IDT xGenExome Research Panel v1.0捕獲,Target Region 39M, Probe Region 51M,CDS Region 33.52M;
HiSeq X-TEN,af選擇0.02 cut off,再過濾。

DC20030078 is 100% Tumor sample and DC20030079 is 100% Normal sample.

 

 

 

Cut off =1%

Cut off =2%

Cut off =3%

Cut off =4%

Cut off =5%

Mutation Number

769

768

734

720

713

TMB value

22.94

22.91

21.90

21.48

21.27

Data Download

DC20030078.filter.0.0.01.tag.maf

DC20030078.filter.0.0.02.tag.maf

DC20030078.filter.0.0.03.tag.maf

DC20030078.filter.0.0.04.tag.maf

DC20030078.filter.0.0.05.tag.maf

 

 
 
 
 

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